Jewish healthy participants, is considered

The cases consisted of 23

The Israeli Jewish patients with histologically

confirmed squamous cell carcinoma

cervix. The group of 162 randomly chosen Israeli

Jewish healthy participants, considered to be

represent the general population, consisting

controls. Germline polymorphism of p53 in

72 codon was identified by PCR in DNA obtained from blood samples taken from each subject. Homozygous arginine was found in 34. 8%

and only 14. 8% in the control group. This difference is

was statistically significant (p = 0. 01).

Frequency of homozygous arginine polymorphism

in the control group was lower than in any other

people are still reported. It was the

significantly more common among those of North

African than among those of different origins (30 3%

8 vs. 10%, .. P 0 01).. We can assume that

People have two copies of each gene, polymorphism means that a single gene is slightly different from the others. Open reading frames is

specific gene levaquin 250 mg segment, which serves as a guide for cells

synthesize protein. Proteins consist of amino acids (there are 20 different amino acids)

, which link together to form a chain, which can then tie knots to form

three-dimensional biomolecule. Proteins are the building blocks of life,

and include enzymes, contractile fibers (in the cells, especially muscle), and

structural fibers. Proteins can be combined with other molecules, such

in the form of fats and sugars. Homozygous arginine polymorphism at codon 72 indicates that the two alleles

(two copies of DNA encoding the same protein), homozygous, or code for the

the same amino acid (arginine) at position number 72 to amino acid

of protein of p53.